How do I call python program (which has command line arguments) from PHP or Javascript?

My Python Program is,

from xbee import ZigBee
import serial
import sys

sPort = serial.Serial("/dev/ttyAMA0", 9600)
xbee = ZigBee(sPort)

targStr = sys.argv[1]
data = str(targStr)
print (data)
destAdd = "\x00\x13\xa2\x00\x40\xa9\xcc\xad"
xbee.send("tx",dest_addr_long=destAdd,dest_addr="\xff\fe",data=data)
print ("Sent!")

When I execute this python program on linux shell, it works all great! How do execute this program on certain event from HTML Page (Either using Javascript, AJAX or PHP) ?